APStracts (ISSN 1080-4757) Vol. 5, 1998

The American Physiological Society

• Nk1 receptor activation prevents hydrocarbon-induced lung injury in mice. Robledo, Raymond F., and Mark L. Witten. 1Department of Pathology, the University of Vermont, Burlington, Vermont, USA 05405-0068; and 2Department of Pediatrics, University of Arizona, Tucson, Arizona, USA 85724-5073 APStracts 5:0220L, 1998.
• Divergent differentiation pathways in cultured airway smooth muscle: induction of a subset of functionally contractile myocytes . Halayko, Andrew J., Blanca Camoretti-Mercado, Sean M. Forsythe, Joaquim E. Vieira, Richard W. Mitchell, Mark E. Wylam, Mark B. Hershenson, and Julian Solway. Section of Pulmonary and Critical Care Medicine, Department of Medicine, University of Chicago, Chicago, IL 60637 APStracts 5:0221L, 1998.
• Mediators of alkalosis-induced relaxation in pulmonary arteries from normoxic and chronically hypoxic piglets. Gordon, John B., Ted R. Halla, Candice D. Fike, and Jane A. Madden. Departments of Pediatrics and Neurology, Medical College of Wisconsin and Zablocki VAMC, Milwaukee, WI 53226 APStracts 5:0222L, 1998.
• Potassium channel blockade inhibits shear stress-induced pulmonary vasodilation in the ovine fetus. Storme, Laurent, Robyn L. Rairigh, Thomas A. Parker, David N. Cornfield, John P. Kinsella, Steven H. Abman. Service de Medecine Neonatale1, Hospital Jeanne de Flandre, CHRU de Lille, FRANCE; Pediatric Heart Lung Center2, Department of Pediatrics, University of Colorado School of Medicine, Denver, Colorado, USA; and Department of Pediatrics3, University of Minnesota School of Medicine, Minneapolis, Minnesota, USA APStracts 5:0223L, 1998.
• Egf activates erbb2 and stimulates phosphatidylinositol 3-kinase in human airway smooth muscle cells. Krymskaya, Vera P., Rebecca Hoffman, Andrew Eszterhas, Sibyl Kane, Vincenzo Ciocca, and Reynold A. Panettieri, Jr. Pulmonary and Critical Care Division, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 APStracts 5:0224L, 1998.
• Alterations in lung expansion affects surfactant protein-a, -b and -c mrna levels in fetal sheep. Lines, A., L. Nardo, I. D. Phillips, F. Possmayer and S. B. Hooper. Department of Physiology, Monash University, Clayton, 3168, Victoria, Australia, 1Department of Obstetrics and Gynaecology, University of Western Ontario, London, Ontario, N6A 5A5, Canada APStracts 5:0225L, 1998.
• The effects of fluoxetine, phentermine and venlafaxine on pulmonary artery pressure and electrophysiology.. , . Departments of Physiology1 and Medicine, VA Medical Center and University of Minnesota, Minnesota 55417 and Department of Medicine2, Division of Cardiology, University of Alberta, Edmonton, Canada. APStracts 5:0226L, 1998.
• Proline in vasoactive peptides: consequences for peptide hydrolysis in the lung. Merker, Marilyn P., Said H. Audi, Becky M. Brantmeier, Kasem Nithipatikom, Robert S. Goldman, David L. Roerig, and Christopher A. Dawson . Departments of Anesthesiology, Pharmacology/Toxicology and Physiology, Medical College of Wisconsin, Milwaukee, WI 53226; Department of Biomedical Engineering, Marquette University, Milwaukee, WI 53233; and Veterans Administration Medical Center, Milwaukee, WI 53295 APStracts 5:0227L, 1998.
• Nitric oxide participates in early events associated with nnmu -induced acute lung injury in rats.. Cruz, Wilhelm S., John A. Corbett, William J. Longmore, and Michael A. Moxley. Edward A. Doisy Department of Biochemistry and Molecular Biology, St. Louis University School of Medicine, St. Louis, MO 63104-1079 APStracts 5:0228L, 1998.
• Emap ii: a modulator of neovascularization in the developing lung.. Schwarz, Margaret, Matt Lee, Fangrong Zhang, Jingsong Zhao, Yangsun Jin, Susan Smith, Janki Bhuva, David Stern, David Warburton, and Vaughn Starnes. Childrens Hospital Research Institute Los Angeles, Developmental Biology and Cardiothoracic Surgery Program, Los Angeles CA. 90027 and *Columbia University Department of Physiology and Cellular Biophysics, New York, NY 10032. APStracts 5:0229L, 1998.
• Lamellar body exocytosis in alveolar type ii cells revealed by cell capacitance and fluorescence measurements. Mair, Norbert, Thomas Haller, and Paul Dietl. Department of Physiology, University of Innsbruck, A-6020 Innsbruck, Austria APStracts 5:0230L, 1998.
• Chronic hypoxia augments endothelin b receptor-mediated vasodilation in isolated perfused rat lungs. Muramatsu, Masashi, Masahiko Oka, Yoshiteru Morio, Sanae Soma, Hideki Takahashi, and Yoshinosuke Fukuchi. Department of Respiratory Medicine, Juntendo University School of Medicine, Tokyo 113-0033, Japan APStracts 5:0231L, 1998.
• The effects of fluoxetine, phentermine and venlafaxine on pulmonary artery pressure and electrophysiology.. , . Departments of Physiology1 and Medicine, VA Medical Center and University of Minnesota, Minnesota 55417 and Department of Medicine2, Division of Cardiology, University of Alberta, Edmonton, Canada. APStracts 5:0232L, 1998.
• Production of interferon- by lung lymphocytes in hiv-infected individuals. Iii, Homer L. Twigg, Blake A. Spain, Diaa M. Soliman, Kenneth Knox, Richard A. Sidner, Carol Schnizlein-Bick, David S. Wilkes, and Gary K. Iwamoto. Department of Medicine, Divisions of Pulmonary/Critical Care Medicine and Infectious Diseases, and Department of Surgery, Indiana University Medical Center, Indianapolis, IN 46202. APStracts 5:0233L, 1998.
• Effect of azelastine on platelet activating factor-induced microvascular leakage in the rat airways. Tamaoki, Jun, Isao Yamawaki, Etsuko Tagaya, Mitsuko Kondo, Kazutetsu Aoshiba, Junko Nakata, and Atsushi Nagai. First Department of Medicine, Tokyo Women's Medical College, Tokyo 162, Japan APStracts 5:0234L, 1998.
• Pirfenidone inhibits pdgf isoforms in the bleomycin hamster model of lung fibrosis at the translational level. Gurujeyalakshmi, G., M. A. Hollinger, and S. N. Giri. Department of Molecular Biosciences, School of Veterinary Medicine; and Department of Medical Pharmacology and Toxicology, School of Medicine, University of California, Davis, CA. APStracts 5:0235L, 1998.
• Endothelin-1 is elevated in monocrotaline pulmonary hypertension. Frasch, H. Frederick, Carol Marshall, and Bryan E. Marshall. Center for Anesthesia Research Hospital of the University of Pennsylvania Philadelphia, PA 19104-4283 APStracts 5:0236L, 1998.
• Determination of low-molecular mass antioxidant concentrations in human respiratory tract lining fluids. Van, Albert, Der Vliet, Charles A. O'neill, Carroll E. Cross, John M. Koostra, William G. Volz, Barry Halliwell and Samuel Louie. 1Division of Pulmonary/Critical Care Medicine, University of California, Davis, Medical Center, Sacramento, CA 95817, 2Toxicology Department, Genentech, Inc., 1 DNA Way, So. San Francisco, CA 94080. 3International Antioxidant Research Centre, Pharmacology Group, King's College, Manresa Road, London, SW3 6LX, U.K., and 4Center for Comparative Respiratory Biology and Medicine, Department of Internal Medicine, 1121 Surge I Annex, University of California, Davis, CA 95616. APStracts 5:0237L, 1998.
• Nitric oxide synthase isoform expression in the developing lung epithelium. Sherman, Todd S., Zhong Chen, Ivan S. Yuhanna, Kim S. Lau-, Linda R. Margraf#, Philip W. Shaul. Departments of Pediatrics*, Physiology-, and Pathology#, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75235 APStracts 5:0238L, 1998.
• The role of neutrophils and [alpha]-1-antitrypsin in coal and silica-induced connective tissue breakdown. Zay, K., S. Loo, C. Xie, D.v. Devine, J. Wright, A. Churg. Department of Pathology, University of British Columbia, Vancouver, BC Canada APStracts 5:0239L, 1998.
• O3-induced inflammation in prepregnant, pregnant and lactating rats correlates with o3 dose estimated by 18o. Gunnison, Albert F., and Gary E. Hatch. 1Nelson Institute of Environmental Medicine, New York University Medical Center, 550 First Ave., New York, N.Y. 10016. 2Pulmonary Toxicology Branch, Experimental Toxicology Division, United States Environmental Protection Agency, Research Triangle park, N.C. 27711. APStracts 5:0240L, 1998.
• Glucocorticoid response elements lying far upstream and within the first intron of rat gs repress expression in the absence of hormone. Chandrasekhar, S., Ph. D., Wiley W. Souba, M. D., Sc. D. and Steve F. Abcouwer, Ph. D. Surgical Oncology Research Laboratories, Massachusetts General Hospital, Department of Surgery, Harvard Medical School, Boston, MA 02114-2696 APStracts 5:0241L, 1998.
• Protective effects of transient ho-1 overexpression on susceptibility to oxygen toxicity in lung cells. Suttner, Denise M., M. D., Kunju Sridhar, Ph. D., Christen S. Lee, B. S., Toshiya Tomura, M. D., Thomas N. Hansen, M. D._ and Phyllis A. Dennery, M. D. Department of Pediatrics, Stanford University School of Medicine, Stanford, CA *Department of Pediatrics, Baylor College of Medicine, Houston, TX and _Department of Pediatrics,Ohio State University, Columbus OH APStracts 5:0242L, 1998.
• Variable expression of endothelial no synthase in three forms of rat pulmonary hypertension. Tyler, Robert C., Masashi Muramatsu, Steven H. Abman, Thomas J. Stelzner, David M. Rodman, Kenneth D. Bloch and Ivan F. McMurtry. *Cardiovascular Pulmonary Research Laboratory & #Department of Pediatrics, University of Colorado Health Sciences Center, Denver, CO 80262 and d Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129 APStracts 5:0243L, 1998.
• Critical role of glass fiber length in tnf production and transcription factor activation in macrophages. Ye, Jianping, Xianglin Shi, William Jones, Yon Rojanasakul, Ningli Cheng, Diane Schwegler-Berry, Paul Baron, Gregory J. Deye, Changlong Li and Vincent Castranova. 1Health Effects Laboratory Division, 2Division of Respiratory Disease Studies, and 4Division of Physical Sciences and Engineering, National Institute for Occupational Safety and Health, Morgantown, WV and Cincinnati, OH; 3Department of Basic Pharmaceutical Sciences, West Virginia University, Morgantown, WV 26506 APStracts 5:0244L, 1998.
• Localization of a candidate surfactant convertase to type ii cells, macrophages and surfactant subfractions.. Clark, Howard, Lennell Allen, Erin Collins, Frederick Barr, Leland Dobbs, Gunther Putz, Jon Goerke, and Samuel Hawgood. Cardiovascular Research Institute and Departments of Pediatrics, University of California San Francisco, San Francisco, CA 94118 -1245 APStracts 5:0245L, 1998.
• Airway synthesis of 20-hydroxyeicosatetraenoic acid: metabolism by cyclooxygenase to a bronchodilator.. Jacobs, Elizabeth R., M. D, Richard M. Effros, M. D, John R. Falck, Ph. D., K. Malla Reddy, Ph. D., William B. Campbell, Ph. D. and Daling Zhu, M. D. Ph. D. Department of Physiology, Cardiovascular Research Center, Medical College of Wisconsin, Department of Medicine, Medical College of Wisconsin, Department of Pharmacology and Toxicology, Medical College Wisconsin, Department of Biochemistry, University of Texas Southwestern Medical Center APStracts 5:0246L, 1998.
• Inhibition of platelet derived growth factor stimulated human airway smooth muscle proliferation by type 3 selective phosphodiesterase inhibition. Billington, Charlotte K, Sunil K Joseph, Caroline Swan, Mark Gh Scott, Timothy M Jobson, and Ian P Hall. Division of Therapeutics, University Hospital, Nottingham, United Kingdom APStracts 5:0247L, 1998.
• Inhibition of the hsp-b promoter in respiratory epithelial cells by a dominant negative retinoic acid receptor. Ghaffari, Manely, Jeffrey A. Whitsett, and Cong Yan. Division of Pulmonary Biology, Children's Hospital Medical Center, Cincinnati, Ohio 45229-3039 APStracts 5:0248L, 1998.
• Effects and interactions of opioids on cigarette smoke-induced plasma exudation in guinea pig bronchi in vivo. Lei, Yu-Hong, and Duncan F. Rogers. Thoracic Medicine, National Heart & Lung Institute (Imperial College), APStracts 5:0249L, 1998.
• Tnfa increases ceramide without inducing apoptosis in alveolar type ii epithelial cells. Mallampalli, Rama K., Erik J. Peterson, Aaron Brent Carter, Ronald G. Salome, Satya N. Mathur, and Gary A. Koretzky. Department of Internal Medicine and the Department of Veterans Affairs Medical Center, The University of Iowa College of Medicine, Iowa City, IA 52242 APStracts 5:0250L, 1998.
• Critical role of glass fiber length in tnf production and transcription factor activation in macrophages. Ye, Jianping, Xianglin Shi, William Jones, Yon Rojanasakul, Ningli Cheng, Diane Schwegler-Berry, Paul Baron, Gregory J. Deye, Changlong Li and Vincent Castranova. 1Health Effects Laboratory Division, 2Division of Respiratory Disease Studies, and 4Division of Physical Sciences and Engineering, National Institute for Occupational Safety and Health, Morgantown, WV and Cincinnati, OH; 3Department of Basic Pharmaceutical Sciences, West Virginia University, Morgantown, WV 26506 APStracts 5:0251L, 1998.
• Tnf-a upregulates gia and gqa protein expression and function in human airway smooth muscle cells. Hotta, Kunihisa, Charles W. Emala, and Carol A. Hirshman. Department of Anesthesiology, College of Physicians & Surgeons at Columbia University, New York, NY 10032 APStracts 5:0252L, 1998.
• Nitric oxide-mediated regulation of transepithelial sodium and chloride transport in murine nasal epithelium. Elmer, Heather L., Kristine G. Brady, Mitchell L. Drumm and Thomas J. Kelley. Departments of Pediatrics1, Genetics and Center for Human Genetics2, and Physiology and Biophysics3, Case Western Reserve University, 8th floor BRB, 10900 Euclid Avenue, Cleveland, Ohio 44106-4948 APStracts 5:0253L, 1998.