APStracts (ISSN 1080-4757) Vol. 5, 1998

The American Physiological Society

• Pronase destroys the lipopolysaccharide receptor cd14 on kupffer cells.. Ikejima, Kenichi, Nobuyuki Enomoto, Vitor Seabra, Ayako Ikejima, David A. Brenner and Ronald G. Thurman. ]1Laboratory of Hepatobiology and Toxicology, Department of Pharmacology and 2Division of Digestive Diseases and Nutrition, Department of Medicine, University of North Carolina at Chapel Hill, NC. APStracts 5:0327G, 1998.
• Diazepam-binding inhibitor33-50 elicits ca2+ oscillation and cck secretion in stc-1 cells via l-type ca2+ channels. Yoshida, Hitoshi, Yasuhiro Tsunoda, and Chung Owyang. Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109 APStracts 5:0328G, 1998.
• Autocrine and paracrine actions of intestinal fibroblast-derived insulin-like growth factors (igfs). Simmons, James G., Jolanta B. Pucilowska, and P. Kay Lund,. Department of Physiology1 and Center for Gastrointestinal Biology and Disease2, The University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7545 APStracts 5:0329G, 1998.
• Fas activates the jnk pathway in human colonic epithelial cells: lack of a direct role in apoptosis. Abreu-Martin, Maria T., Andrew A. Palladino, Mary Faris_, Nelson M. Carramanzana, Andr[acute]e E. Nel_, Stephan R. Targan. *Inflammatory Bowel Disease Center, Cedars-Sinai Medical Center, Los Angeles, California, _Division of Clinical Immunology and Allergy, Department of Medicine, Jonsson Cancer Center, UCLA School of Medicine, Los Angeles, California APStracts 5:0330G, 1998.
• Physiological chemistry of nitric oxide and its metabolites: implications in inflammation. Grisham, Matthew B., David Jourd_heuil, and David A. Wink. Department of Molecular and Cellular Physiology, LSU Medical Center, Shreveport, LA 71130 and *Radiation Biology Branch, National Cancer Institute, Bethesda, MD 20892. APStracts 5:0331G, 1998.
• The epithelial sodium channel and its implication in human diseases. Hummler, Edith, and Jean-Daniel Horisberger. Institut de Pharmacologie et de Toxicologie, Universit[acute]e de Lausanne, Switzerland APStracts 5:0332G, 1998.
• Increased gastrointestinal permeability is an early lesion in the spontaneously diabetic bb rat. Meddings, J. B., J. Jarand, S. J. Urbanski, J. Hardin, and D. G. Gall. Gastrointestinal Research Group, University of Calgary APStracts 5:0333G, 1998.
• Secretagogue-induced digestive enzyme activation and cell injury in rat pancreatic acini. Saluja, A. K., L. Bhagat, H. S. Lee, M. Bhatia, J. L. Frossard, and M. L. Steer. Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Digestive Diseases Center and Harvard Medical School, Boston, MA 02215 APStracts 5:0334G, 1998.
• Aberrant expression of gastrin-releasing peptide and its receptor by well differentiated colon cancers in humans.. Carroll, Robert E., Kristina A. Matkowskyj, Subrata Chakrabarti, Thomas J. McDonald, Richard V. Benya. 1Both authors contributed equally to this work. 2Departments of Medicine and 3Pathology, 4University of Illinois at Chicago; 5Chicago Veterans Administration Medical Center (West Side Division), Chicago, Illinois 60612; and (6) University of Western Ontario, London, Ontario, Canada. APStracts 5:0335G, 1998.
• Tgf-[beta]1 in liver fibrosis: an inducible transgenic mouse model to study liver fibrogenesis.. Kanzler, Stephan, _, Ansgar W Lohse _, Andrea Keil _, J[umlaut]urgen Henninger _, Hans P Dienes #, Peter Schirmacher #, Stefan Rose-John _, Karl H Meyer Zum B[umlaut]uschenfelde _, Manfred Blessing _. . Boehringer Ingelheim Research Group *, I. Department of Medicine, University of Mainz _, Department of Pathology #, University of Cologne, Germany. APStracts 5:0336G, 1998.
• Interaction of asparagine and epidermal growth factor in the regulation of ornithine decarboxylase in iec-6 cells. Ray, Ramesh M., Mary Jane Viar, Tarun B. Patel and Leonard R. Johnson. Department of Physiology and Biophysics, and Pharmacology*, University of Tennessee, Memphis, College of Medicine APStracts 5:0337G, 1998.
• Hepatocyte nuclear factor 4 regulates intestinal expression of the guanylin/heat-stable toxin receptor (gc-c). Swenson, E. Scott, Ph. D., Elizabeth A. Mann, Ph. D., M. Lynn Jump, M. S., and Ralph A. Giannella, M.d. Division of Digestive Diseases, VA Medical Center and University of Cincinnati, College of Medicine, Cincinnati, OH 45267 APStracts 5:0338G, 1998.
• Cholic acid aids absorption, biliary secretion and phase transitions of cholesterol in murine cholelithogenesis. Wang, David Q.-H., Frank Lammert, David E. Cohen, Beverly Paigen, and Martin C. Carey. Department of Medicine, Harvard Medical School, Gastroenterology Division, Brigham and Women's Hospital and Harvard Digestive Diseases Center, Boston, MA 02115; and * The Jackson Laboratory, Bar Harbor, ME 04609 APStracts 5:0339G, 1998.
• Epidermal growth factor regulates fatty acid uptake and metabolism in caco2 cells. Darimont, Christian, Nathalie Gradoux, and Alain De Pover. Metabolic and Cardiovascular Diseases, Novartis Pharma AG, CH-4002 Basel, Switzerland. APStracts 5:0340G, 1998.
• Evidence of t cell receptor b-chain patterns in inflammatory and non-inflammatory bowel disease states. Saubermann, Lawrence J., Christopher Sj. Probert, Andreas D. Christ, Andreas Chott, Jerrold R. Turner, A. Christopher Stevens, Steven P. Balk, Richard S. Blumberg. 1Division of Gastroenterology, Brigham & Women's Hospital, Boston, MA, 02115; 2University of Bristol, Bristol, UK; BS2 8HW, 3Universitaetsspital, Zurich, Switzerland; CH-8091, 4Universitit Wein, Vienna, Austria, 1090 ; 5Wayne State Medical Center, Detroit, MI; 48201, 6Beth Israel Deaconess Medical Center, Boston, MA, 02115. APStracts 5:0341G, 1998.
• Attenuation of intestinal ion transport by enteropathogenic e. coli is not due to decreased cl- secretion. Hecht, Gail, and Athanasia Koutsouris. Department of Medicine (Section of Digestive and Liver Diseases), University of Illinois and West Side VAMC, Chicago, IL 60612 APStracts 5:0342G, 1998.
• Regulation of igf binding protein-1 in hepg2 cells by cytokines and reactive oxygen species. Lang, Charles H., Gerald J. Nystrom, and Robert A. Frost. Departments of Cellular and Molecular Physiology and Surgery, Pennsylvania State College of Medicine, Hershey, PA 17033 APStracts 5:0343G, 1998.
• Rat hepatic endothelial cell glutamine transporter and glutaminase isozyme expression contrasts with parenchymal cells. Lohmann, R[umlaut]udiger, Wiley W. Souba, and Barrie P. Bode. Division of Surgical Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114-2696 APStracts 5:0344G, 1998.
• Evidence for an anion exchange mechanism for uptake of conjugated bile acid from the rat jejunum. Amelsberg, Andree, Christina Jochims, Claus Peter Richter, Rolf Nitsche, and Ulrich R. F[diaeresis]olsch. From the Department of Medicine, Christian-Albrechts-University Kiel, Germany APStracts 5:0345G, 1998.
• 1,25-dihydroxyvitamin d3 and tpa activate phospholipase d in caco-2 cells: role of pkc-. Khare, Sharad, Marc Bissonnette, Beth Scaglione-Sewell, Ramesh K. Wali, Michael D. Sitrin, and Thomas A. Brasitus . Department of Medicine, University of Chicago APStracts 5:0346G, 1998.
• 1,25-dihydroxyvitamin d3, but not tpa activates pld in caco-2 cells via pp60c-src and rhoa. Khare, Sharad, Marc Bissonnette, Ramesh Wali, Susan Skarosi, Gerry R. Boss, Friederike C. Von Lintig, Beth Scaglione-Sewell, Michael D. Sitrin and Thomas A. Brasitus . _Departments of Medicine, University of Chicago* and University of California, San Diego+ APStracts 5:0347G, 1998.
• Regional effects of cholecystokinin octapeptide on colonic phasic and tonic motility in healthy humans.. Coffin, Benoit, Sophie Fossati, Bernard Flouri[acute]e, Marc L[acute]emann, Pauline Jouet, Claire Franchisseur, Raymond Jian, and Jean-Claude Rambaud. From the Services de Gastro-ent[acute]erologie, H[circumflex]opital Saint-Lazare and H[circumflex]opital Saint-Louis, PARIS, FRANCE. APStracts 5:0348G, 1998.
• Differential activation of phosphoinositide 3kinase (pi3k) by endothelin and ceramide in colonic smooth muscle cells. Su, Xuehui, Pinglang Wang, Adenike Ibitayo, and Khalil N. Bitar. Department of Pediatrics, University of Michigan Medical Center, Ann Arbor, Michigan 481090656 APStracts 5:0349G, 1998.
• Excretion of progastrin products in human urine. Hansen, C. Palnaes, J. P. Goetze, F. Stadil, and J. F. Rehfeld. Departments of Gastrointestinal Surgery and Clinical Biochemistry, Rigshospitalet, University of Copenhagen, DK-2100 Copenhagen, Denmark APStracts 5:0350G, 1998.
• Endogenous interstitial adenosine in isolated myenteric neural networks varies inversely with prevailing po2. Deshpande, N. A., T. J. McDonald, and M. A. Cook. 1Department of Pharmacology and Toxicology, 2Department of Medicine and 3Robarts Research Institute, University of Western Ontario, London, Ontario, Canada N6A 5C1 APStracts 5:0351G, 1998.
• Peripheral urocortin delays gastric emptying: role of crf receptor -2. Nozu, Tsukasa, Vicente Martinez, Jean Rivier and Yvette Tach[acute]e. 1Center for Ulcer Research and Education: Digestive Diseases Research Center, West Los Angeles VA Medical Center, Digestive Disease Division, Department of Medicine and Brain Research Institute, UCLA School of Medicine, Los Angeles, California 90073 and 2Clayton Foundation Laboratories for Peptide Biology, The Salk Institute for Biological Studies, La Jolla, California 92038 APStracts 5:0352G, 1998.
• Validation of a novel luminal flow velocimeter with video fluoroscopy and manometry in the human oesophagus.. Andrews, Jm, H Nathan, Ch Malbert, Mamt Verhagen, M Gabb, Gs Hebbard, D Kilpatrick, S Macdonald, Ck Rayner, S Doran, T Omari, E O'young, C Frisby, Rj Fraser, M Schoeman, M Horowitz and J Dent. Departments of Medicine1, Gastrointestinal Medicine2 and Radiology3 Royal Adelaide Hospital, Adelaide, SA, 5000, Australia; Station de Reserches Porcines, INRA, Saint-Gilles, France4; Gastrointestinal Motility Unit, University Hospital, Utretch, The Netherlands5; Department of Gastroenterology, Women_s and Children_s Hospital, Adelaide, SA, 5000, Australia6; Department of Cardiology, Royal Hobart Hospital, Hobart, Tas, Australia7. APStracts 5:0353G, 1998.
• Microvascular perfusion deficits are not a prerequisite for mucosal injury in septic rats. Nevi[grave]ere, R. R., M. L. Pitt-Hyde, R. D. Piper, W. J. Sibbald, and R. F. Potter. London Health Sciences Centre Research Incorporated, and the Departments of Medical Biophysics, and Medicine, University of Western Ontario, London, Ontario, Canada, N6A 4G5 APStracts 5:0354G, 1998.
• An assessment of the mechanism of juxtacrine activation and adhesion of leukocytes in liver microcirculation.. Carvalho-Tavares, Juliana, Alison Fox-Robichaud, and Paul Kubes. Immunology Research Group, University of Calgary, Calgary, Alberta, T2N 4N1 APStracts 5:0355G, 1998.
• Intravenous glycine improves survival in rat liver transplantation. Schemmer, Peter, Blair U. Bradford, Michelle L. Rose, Hartwig Bunzendahl, James A. Raleigh, John J. Lemasters and Ronald G. Thurman. 1Lab. of Hepatobiology and Toxicology, Dept. of Pharmacology, 2Dept. of Surgery, 3Dept. of Radiation Oncology and 4Dept. of Cell Biology and Anatomy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA APStracts 5:0356G, 1998.
• Mechanisms underlying the antiinflammatory action of central corticotropin-releasing factor.. Casadevall, Maria, Esteban Saperas, Juli[acute]an Pan[acute]es, Azucena Salas, Donald C. Anderson, Juan R. Malagelada and Josep M. Piqu[acute]e. 1Gastroenterology Department, Institut Cl[acute]inic de Malalties Digestives, Hospital Cl[acute]inic, University of Barcelona, Spain. 2 Digestive System Research Unit. Hospital Vall d_Hebr[acute]on, Barcelona, Spain. 3 Discovery Research, Pharmacia-Upjohn Laboratories, Kalamazoo, MI. APStracts 5:0357G, 1998.
• Cholinergic and gabaergic regulation of nitric oxide synthesis in the guinea-pig ileum. Hebei[beta], Katalina, and Heinz Kilbinger. Department of Pharmacology, University of Mainz, D-55101 Mainz, Germany APStracts 5:0358G, 1998.
• Nitric oxide protects in intestinal inflammation1. Lefer, Allan M., and David J. Lefer. Department of Physiology, Jefferson Medical College, Thomas Jefferson University, Philadelphia, PA 19107, Phone: (215) 503-7760, Fax: (215) 503-2073, and Department of Physiology, Louisiana State University Medical Center, Shreveport, LA 71130, Phone: (318) 675 -6974, Fax: (318) 675-4217, APStracts 5:0359G, 1998.
• Ethanol modulation of intestinal epithelial tight junction barrier.. Ma, Thomas Y., Don Nguyen, Vuong Bui, Hanh Nguyen, and Neil Hoa. Division of Gastroenterology, Department of Medicine, DVA Medical Center, Long Beach, CA, University of California, Irvine APStracts 5:0360G, 1998.
• Effects of ibmx on norepinephrine-induced vasoconstriction in small mesenteric arteries. Taylor, Mark S., Hong Gao, Jason D. Gardner, and Joseph N. Benoit. Department of Physiology, University of South Alabama College of Medicine, Mobile, AL 36688 APStracts 5:0361G, 1998.
• Secretagogue-induced digestive enzyme activation and cell injury in rat pancreatic acini. Saluja, A. K., L. Bhagat, H. S. Lee, M. Bhatia, J. L. Frossard, and M. L. Steer. Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Digestive Diseases Center and Harvard Medical School, Boston, MA 02215 APStracts 5:0362G, 1998.
• Paracellular glucose transport plays a minor role in the unanesthetized dog. Lane, John S., Edward E. Whang, David A. Rigberg, Oscar J. Hines, David Kwan, Michael J. Zinner, David W. McFadden, Jared Diamond, Stanley W. Ashley. Department of Surgery, 2Brigham and Women's Hospital, Boston, Massachusetts and Departments of 1Surgery and Physiology, UCLA Medical Center, Los Angeles, California APStracts 5:0363G, 1998.